Facing a Failure in The in Vitro Fertilization Treatment

“What You should Know”

Infertility and In Vitro Fertilization (IVF): Keeping Hope Alive

We understand that this can be a challenging time for those dealing with fertility issues.

We know that approximately 17% of couples of reproductive age face this challenge. In Vitro Fertilization (IVF), whether with one’s own eggs or donated eggs (ovodonation), is often the best option to fulfill the dream of having a baby at home. However, it’s important to know that these treatments may not succeed in every case.

Feeling overwhelmed and challenged if you’ve had difficulties with IVF is normal. But remember that hope is crucial in this situation.

In the assisted conception process, perseverance and resilience are key. Each attempt, while emotionally taxing, brings you closer to your goal of having a family. Obstacles are a part of this journey, but they also provide opportunities for learning, growth, and adaptation.

It’s important to note that science and medicine are constantly advancing, meaning there are always new perspectives and options. Despite the difficulties, you can’t predict when your next attempt might succeed.

Trust in your specialized medical professionals, who are committed to helping you achieve your dream of becoming parents. Emotional support from your loved ones is also crucial because you’re not alone in this. There are communities and resources available to support you at every stage of the process.

The bravery and determination you’ve shown deserve recognition and admiration. Together, you can overcome this challenge and achieve your dream of starting a family. Keep the faith and determination, as each day brings you closer to your goal.

Always remember that hope is the force that propels you forward. We are here to support you every step of the way and have full confidence in your ability to overcome obstacles and reach the happiness you so deserve. Let’s keep moving forward together toward a future filled with joy and love.

Are there signs that predict a negative result in IVF?

The only reliable way to determine the success or failure of assisted reproductive treatment is through a pregnancy test, either through a urine test or, more accurately, through a blood test to detect the Beta hormone (BhCG) level.

It’s important to distinguish between factors that should be evaluated before treatment and those that could influence future attempts after IVF failure.

Key Factors Before Treatment

Maternal Age

Aging can affect the quantity and quality of eggs.

Male Factor Issues

Alterations in the mobility, quantity, and shape of sperm.

Body Mass Index (BMI)

High BMI, especially above 30, can hinder fertilization and increase the risk of miscarriage in both women and men.

Cause of Infertility

Whether it’s primary or secondary.


Can affect egg quality.

Toxic Factors

Substance use like tobacco and alcohol, as well as exposure to harmful environmental factors, can impact treatment outcomes.

Unexplained Infertility

When no specific cause is found.

Intrauterine Anatomic Abnormalities

Uterine problems that hinder pregnancy, such as hydro­salpinx, and bicorn uterus.

Key factors after IVF failureFactores después de un fallo en la FIV

Ovarian Factor

Ovarian response in previous cycles can guide the customization of future attempts.

Endometrial Factor

Uterine issues, endometrial problems, or immunological factors can influence implantation. Specific therapies like ERA or Endometrio may be recommended for personalized transfers with altered implantation windows.

Seminal Quality

Parameters like sperm quantity and quality can affect fertilization.

Embryo Quality

High-quality embryos have higher success rates. Genetic testing can help identify abnormalities.

Laboratory Quality Control

A high-quality IVF lab is essential for embryo development.

Embryologists Experience

The laboratory team’s expertise is crucial.

When to try a new IVF after a failed cycle.

If another ovarian stimulation is planned, it’s recommended to wait 2 to 3 months to allow the ovaries to recover.

Alternatively, if a frozen embryo transfer is planned, there’s no need to wait this long, as the ovaries are not involved.

Emotional support after a negative IVF result.

A negative result after investing time, energy, and emotions can be devastating.

It’s important to seek emotional support to cope with this frustrating moment and move forward on the journey to parenthood.

We are empathetic to every situation that a couple with infertility goes through, we have the technology and experience to support your treatment.